This area is reserved for registered users. Please register or login.

Spiolto Respimat – Maintenance bronchodilator treatment to relieve symptoms in adults with COPD

Spiolto Respimat is a fixed dose combination inhalation solution containing a long acting muscarinic receptor antagonist, tiotropium and a long acting beta2-adrenergic agonist, olodaterol (LAMA/LABA) which is delivered via the Respimat soft mist inhaler device.   Muscarinic receptors are more prominent in the central airways while beta2 adrenoceptors have a higher expression level in the peripheral airways. Therefore the combination of a LAMA and a LABA should provide optimal bronchodilatation in all regions of the lungs.   Spiolto is indicated as a maintenance bronchodilator treatment to relieve symptoms in adults with chronic obstructive pulmonary disease (COPD). The recommended dose is…